The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Mar. 28, 2018
Applicant:

Easel Biotechnologies, Llc, Culver City, CA (US);

Inventors:

Yi-Xin Huo, Los Angeles, CA (US);

Benjamin Schilling, Sacramento, CA (US);

Shahrooz Rabizadeh, Culver City, CA (US);

Assignee:

Easel Biotechnologies, LLC, Culver City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 9/88 (2006.01); C12N 9/12 (2006.01); C12P 7/16 (2006.01); C10L 1/00 (2006.01); C12N 15/74 (2006.01); C12P 7/62 (2006.01); C12P 5/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C10L 1/00 (2013.01); C12N 1/20 (2013.01); C12N 9/1205 (2013.01); C12N 15/74 (2013.01); C12P 7/16 (2013.01); C12P 7/625 (2013.01); C12Y 207/01019 (2013.01); C12Y 401/02009 (2013.01); C10L 2200/0469 (2013.01); C10L 2290/26 (2013.01); C12P 5/026 (2013.01); Y02E 50/10 (2013.01);
Abstract

Genetically engineered cells and methods are presented that allow for the production of various value products from CO. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of COfixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.


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