The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2019
Filed:
Oct. 02, 2015
Applicant:
Metabolic Explorer, Saint Beauzire, FR;
Inventors:
Zhen Chen, Beijing, CN;
Feng Geng, Hamburg, DE;
An-Ping Zeng, Rosengarten, DE;
Wanda Dischert, Vic-le-Comte, FR;
Philippe Soucaille, Deyme, FR;
Assignee:
METABOLIC EXPLORER, Saint Beauzire, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 9/06 (2006.01); C12P 7/18 (2006.01); C12P 7/42 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0016 (2013.01); C12N 1/20 (2013.01); C12P 7/18 (2013.01); C12P 7/42 (2013.01); C12Y 104/01002 (2013.01); C12Y 104/01003 (2013.01); C12Y 104/01004 (2013.01);
Abstract
The present invention concerns a method for the production of derivatives of 4-hydroxy-2-ketobutyrate chosen among 1,3-propanediol or 2,4-dihydroxybutyrate by culturing a genetically modified microorganism for the production of the desired derivative of 4-hydroxy-2-ketobutyrate, the microorganism further comprising a gene coding for a mutant glutamate dehydrogenase converting by deamination L-homoserine into 4-hydroxy-2-ketobutyrate. The invention also concerns said genetically modified microorganism.