The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2019
Filed:
Mar. 13, 2014
Applicant:
Dsm Ip Assets B.v., TE Heerlen, NL;
Inventors:
Joshua Trueheart, Somerville, MA (US);
Jessica McGrath, Cambridge, MA (US);
Assignee:
DSM IP Assets B.V., TE Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/22 (2006.01); C12N 9/22 (2006.01); C12Q 1/68 (2018.01); C12N 1/08 (2006.01); C12P 23/00 (2006.01);
U.S. Cl.
CPC ...
C12N 1/08 (2013.01); C12N 9/22 (2013.01); C12P 23/00 (2013.01); C12Y 301/21004 (2013.01);
Abstract
The present invention relates to the use of a thermophilic nuclease for degrading nucleic acids in vivo and/or in situ, wherein the thermophilic nuclease is heterologous to the host cell and is produced by the host rather than being added exogenously. The present invention further relates to a genetically modified cell which was produced according to the above method. The present invention is particularly beneficial in inactivating the biological activity of recombinant DNA in biomass or biomass-derived products.