The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Oct. 31, 2017
Applicant:

Nektar Therapeutics, San Francisco, CA (US);

Inventor:

Xiaoming Shen, Millbrae, CA (US);

Assignee:

Nektar Therapeutics, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 65/333 (2006.01); A61K 31/74 (2006.01); C08G 65/00 (2006.01); C08G 65/48 (2006.01); A61K 47/60 (2017.01); A61K 47/65 (2017.01); A61K 47/68 (2017.01); A61K 47/58 (2017.01);
U.S. Cl.
CPC ...
C08G 65/33396 (2013.01); A61K 31/74 (2013.01); A61K 47/58 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08); C08G 65/00 (2013.01); C08G 65/33337 (2013.01); C08G 65/48 (2013.01);
Abstract

The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.


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