The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2019
Filed:
Mar. 30, 2017
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Suresh Kumar Thallapuranam, Fayetteville, AR (US);
David A. Zaharoff, Morrisville, NC (US);
Srinivas Jayanthi, Fayetteville, AR (US);
Bhanuprasanth Koppolu, Cary, NC (US);
Rebecca Kerr, Fayetteville, AR (US);
Kartik Balachandran, Fayetteville, AR (US);
David S. McNabb, Fayetteville, AR (US);
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
The present invention relates to the development of stable mutants of FGF-1 and FGF-2. In particular, it relates to novel engineered FGF-1 and FGF-2 polypeptides as well as polynucleotides, DNA constructs, and vectors encoding such polypeptides. In another aspect, pharmaceutical compositions and hydrogels including the disclosed polypeptides, polynucleotides, DNA constructs, and vectors are provided. In a still further aspect, methods of treating conditions using the compositions disclosed herein are provided.