The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Jul. 17, 2018
Applicant:

Fujifilm Corporation, Minato-ku, Tokyo, JP;

Inventors:

Hidenobu Kuniyoshi, Ashigarakami-gun, JP;

Daisuke Nakagawa, Ashigarakami-gun, JP;

Takuya Matsumoto, Ashigarakami-gun, JP;

Yuji Yoshimitsu, Ashigarakami-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/10 (2006.01); A61P 35/02 (2006.01); A61K 31/7068 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); A61K 31/7068 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01);
Abstract

Disclosed are a compound and a pharmaceutical composition that exhibit an excellent drug efficacy against a tumor, in particular a tumor which has acquired resistance to gemcitabine. Specifically, provided is a thionucleoside derivative represented by General (in the formula, Rrepresents a hydroxyl group which may be protected, a Calkoxy group which may be substituted, or the like; Rrepresents a Calkoxy group which may be substituted, a Ccycloalkoxy group which may be substituted, or the like; and Rrepresents a hydrogen atom or the like); or a salt thereof. Further, provided is a pharmaceutical composition containing such a thionucleoside derivative or a salt thereof.


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