The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Dec. 13, 2017
Applicant:

Nissan Chemical Corporation, Chuo-ku, JP;

Inventors:

Tsuneo Watanabe, Funabashi, JP;

Keiji Takahashi, Funabashi, JP;

Keishi Hayashi, Funabashi, JP;

Takanori Nakamura, Shiraoka, JP;

Masataka Minami, Funabashi, JP;

Kazunori Kurihara, Funabashi, JP;

Akio Yamamoto, Funabashi, JP;

Takuya Nishimura, Funabashi, JP;

Miyuki Uni, Funabashi, JP;

Toshihiko Kamiyama, Funabashi, JP;

Shunsuke Iwamoto, Funabashi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/519 (2006.01); A61K 31/4375 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61K 31/4375 (2013.01); A61K 31/519 (2013.01); Y02P 20/55 (2015.11);
Abstract

Novel tricyclic compounds which have JAK inhibitory activities are useful for prevention, treatment or improvement of autoimmune diseases, inflammatory diseases and allergic diseases are provided. Novel tricyclic compound represented by the formula (I), the formula (II) or the formula (III) (wherein: each of A, Aand Ais a cyclohexane-1,4-diyl group or the like; each of L, Land Lis a methylene group or the like; each of Xand Xis O or NH; each of Rand Ris a cyano Chaloalkyl group or the like; and Ris an aromatic heterocyclic group), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.


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