The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2019
Filed:
Oct. 04, 2016
Daiichi Sankyo Company, Limited, Tokyo, JP;
U3 Pharma Gmbh, Martinsried, DE;
Thore Hettmann, Martinsried, DE;
Reimar Abraham, Martinsried, DE;
Sabine Blum, Martinsried, DE;
Suguru Ueno, Tokyo, JP;
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
DAIICHI SANKYO EUROPE GMBH, Munich, DE;
Abstract
To provide an antitumor drug having excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. Provided is an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER3 antibody via a linker having a structure represented by the formula: -L-L-L-NH—(CH)n-L-(CH)n-C(═O)— or -L-L-L- (the anti-HER3 antibody is connected to the terminal of L, the antitumor compound is connected to the carbonyl group of —(CH)n-C(═O)— moiety or the C terminal of L, with the nitrogen atom of the amino group at position 1 as a connecting position).