The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Jul. 27, 2016
Applicant:

Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;

Inventor:

Dai Kawamura, Saitama, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/436 (2006.01); A61K 47/26 (2006.01); A61K 9/14 (2006.01); A61K 47/38 (2006.01); A61K 31/7016 (2006.01);
U.S. Cl.
CPC ...
A61K 31/436 (2013.01); A61K 9/14 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01); A61K 31/7016 (2013.01); A61K 2300/00 (2013.01);
Abstract

It is an object of the present invention to provide a pharmaceutical composition which can suppress a reduction in the content of an active ingredient caused by oxidation or decomposition of the rapamycin or a derivative thereof, can ensure long-term stability, and has high safety. The present invention provides a pharmaceutical composition comprising (A) rapamycin or a derivative thereof and (B) trehalose, and a method for producing a pharmaceutical composition comprising rapamycin or a derivative thereof, which comprises adding a solution containing rapamycin or a derivative thereof to sugars having a critical relative humidity at 25° C. of 95% or more.


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