The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Jul. 06, 2017
Applicant:

Yuhan Corporation, Seoul, KR;

Inventors:

Se-Woong Oh, Gyeonggi-do, KR;

Youn Hur, Gyeonggi-do, KR;

Jin-Hwi Park, Gyeonggi-do, KR;

Jae-Eun Joo, Gyeonggi-do, KR;

Ho-Woong Kang, Gyeonggi-do, KR;

Hyok-Jun Cho, Gyeonggi-do, KR;

Eui-Chul Lee, Gyeonggi-do, KR;

Chan-Sun Park, Gyeonggi-do, KR;

Dong-Hyun Kim, Seoul, KR;

Jong-Gyun Kim, Gyeonggi-do, KR;

Su-Youn Nam, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/82 (2006.01); A61K 31/428 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/428 (2013.01); A61P 35/04 (2018.01); C07D 277/82 (2013.01);
Abstract

The present invention provides a benzo[d]thiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzo[d]thiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the benzo[d]thiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.


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