The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2019
Filed:
Oct. 23, 2015
Applicant:
Orca Pharmaceuticals Limited, Abingdon, GB;
Inventors:
Assignee:
ORCA PHARMACEUTICALS LIMITED, Abingdon, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 31/405 (2006.01); A61K 31/416 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/519 (2006.01); A61K 9/00 (2006.01); C07D 209/10 (2006.01); C07D 209/12 (2006.01); C07D 231/56 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/405 (2013.01); A61K 9/0053 (2013.01); A61K 31/404 (2013.01); A61K 31/416 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/519 (2013.01); C07D 209/10 (2013.01); C07D 209/12 (2013.01); C07D 231/56 (2013.01); C07D 401/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention provides compounds of formula (I), wherein A, A, Z, Z, Z, R, R, R, R, R, R, n, p and q are as defined herein. In certain embodiments, the compounds of the invention are RORγt antagonists. In other embodiments, the compounds of the invention are useful in the treatment and/or prevention of inflammatory and autoimmune conditions.