The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Jan. 27, 2014
Applicant:

Hasso-plattner-institut Fuer Softwaresystemtechnik Gmbh, Potsdam, DE;

Inventors:

Hasso Plattner, Schriesheim, DE;

Matthieu-Patrick Schapranow, Berlin, DE;

Emanuel Ziegler, Heidelberg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16B 30/00 (2019.01); G16B 50/00 (2019.01); G16B 45/00 (2019.01);
U.S. Cl.
CPC ...
G16B 30/00 (2019.02); G16B 50/00 (2019.02); G16B 45/00 (2019.02);
Abstract

A high performance, low-cost, gapped read alignment algorithm is disclosed that produces high quality alignments of a complete human genome in a few minutes. Additionally, the algorithm is more than an order of magnitude faster than previous approaches using a low-cost workstation. The results are obtained via careful algorithm engineering of the seeding based approach. The use of non-hashed seeds in combination with techniques from search engine ranking achieves fast cache-efficient processing. The algorithm can also be efficiently parallelized. Integration into an in-memory database infrastructure (IMDB) leads to low overhead for data management and further analysis.


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