The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Apr. 05, 2017
Applicant:
The Chinese University of Hong Kong, Shatin, CN;
Inventors:
Jun Yu, Hong Kong, CN;
Joseph Jao Yiu Sung, Hong Kong, CN;
Simon Siu Man Ng, Hong Kong, CN;
Yujuan Dong, Hong Kong, CN;
Assignee:
The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/574 (2006.01); C12P 19/34 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/00 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57419 (2013.01); C12P 19/34 (2013.01); C12Q 1/6886 (2013.01); C12Q 1/00 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/158 (2013.01); G01N 33/00 (2013.01); G01N 2800/50 (2013.01); G01N 2800/56 (2013.01);
Abstract
The present invention provides a method for diagnosing and determining prognosis of colorectal cancer in a subject by detecting suppressed expression of the VSTM2A gene, which in some cases is due to elevated methylation level in the genomic sequence of this gene. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating colorectal cancer by increasing VSTM2A gene expression or activity.