The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Nov. 30, 2016
Applicant:

Scientific Industries, Inc., Bohemia, NY (US);

Inventors:

Michael Tolosa, Columbia, MD (US);

William Chandler, Oakmont, PA (US);

Douglas J. Koebler, Irwin, PA (US);

Joseph G. Cremonese, Greensburg, PA (US);

Brookman P. March, Casco, ME (US);

Assignee:

Scientific Industries, Inc., Bohemia, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); B01L 3/00 (2006.01); G01N 21/64 (2006.01); G01N 33/483 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); G01N 33/4833 (2013.01); G01N 2201/062 (2013.01);
Abstract

Embodiments of a cell culture monitoring system are disclosed that may include a device having collimating and filtering components to elicit and detect fluorescence from a substrate located within a reaction vessel. The device may be used to detect changes in pH and dissolved oxygen levels in a liquid contained in the reaction vessel due to growth of living cells. Excitation light beams can be generated and collimated by a beam combiner and directed into the reaction vessel so as to be incident upon the substrate to cause the substrate to fluoresce. Some embodiments include use of expected wavelength offsets and shifted filters/mirrors to improve functionality and reduce space of device components.


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