The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Jun. 29, 2017
Applicants:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Los Alamos National Security, Llc, Los Alamos, NM (US);

Inventors:

Eddie W Stover, Fort Pierce, FL (US);

Goutam Gupta, Santa Fe, NM (US);

Guixia Hao, Fort Pierce, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 7/08 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8281 (2013.01); C07K 7/08 (2013.01); C07K 14/415 (2013.01); C07K 2319/00 (2013.01);
Abstract

Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin. Genetically altered plants and their progeny expressing a polynucleotide encoding optimized pro-thionin or optimized thionin resist diseases caused by bacteria.


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