The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Dec. 06, 2011
Applicants:
Judy Lieberman, Brookline, MA (US);
Lee Adam Wheeler, Boston, MA (US);
Inventors:
Judy Lieberman, Brookline, MA (US);
Lee Adam Wheeler, Boston, MA (US);
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/115 (2010.01); A61K 31/713 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); C12N 15/111 (2013.01); C12N 15/1132 (2013.01); C12N 2310/14 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3183 (2013.01); C12N 2310/3519 (2013.01);
Abstract
The invention provides aptamer-gene modulator conjugates, where the aptamer and the gene modulator are linked together. The invention further provides a method for cell-specific delivery of gene modulators to hard to transfect cells such as CD4+ cell.