The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Mar. 03, 2015
Applicant:
Sigma-aldrich Co. Llc, St. Louis, MO (US);
Inventors:
Nan Lin, St. Louis, MO (US);
Joaquina Mascarenhas, St. Louis, MO (US);
Audrey Chang, St. Louis, MO (US);
David Onions, St. Louis, MO (US);
Henry George, St. Louis, MO (US);
Kevin Kayser, St. Louis, MO (US);
Assignee:
SIgma-Aldrich Co. LLC, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0682 (2013.01); C12N 5/00 (2013.01); C12N 9/1051 (2013.01); C12Y 204/01101 (2013.01); C12Y 204/01144 (2013.01); C12Y 204/01155 (2013.01); C12N 2501/724 (2013.01); C12N 2510/02 (2013.01); C12N 2720/12011 (2013.01); C12N 2750/14311 (2013.01);
Abstract
The present invention provides mammalian cell lines that have been genetically engineered causing such cell lines to be resistant to viral entry and/or propagation, and provides methods of using said cell lines to reduce or prevent viral contamination of biologic production systems.