The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Feb. 09, 2015
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Xiao-Dong Chen, San Antonio, TX (US);
Chih-ko Yeh, San Antonio, TX (US);
Joo L. Ong, San Antonio, TX (US);
Assignee:
The Board of Regents of the University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61L 27/38 (2006.01); A61L 27/22 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0633 (2013.01); A61L 27/3813 (2013.01); A61L 27/227 (2013.01); C12N 2501/999 (2013.01); C12N 2533/50 (2013.01); C12N 2533/52 (2013.01); C12N 2533/56 (2013.01);
Abstract
A cell culture system including a silk fibroid scaffold, culture media, and salivary gland cells. The salivary gland cells grown in the tissue culture system have physiological and morphological features like those of in vivo salivary gland cells. The cell culture system can be used to produce a salivary tissue-specific extracellular matrix capable of inducing differentiation of salivary gland cell precursors into salivary gland cells.