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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10377818 B1

PDFFull Text
Date of Patent:
Aug. 13, 2019

Filed:

Jan. 29, 2016

Method of treating glioma

Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Michelle Monje-Deisseroth, Stanford, CA (US);

Humsa S. Venkatesh, Milpitas, CA (US);

Assignee:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Attorneys:

Edward J. Baba

Payal B. Sud

Bozicevic, Field & Francis LLP

Primary Examiner:

Kimberly Ballard

Assistant Examiner:

Stacey N MacFarlane

Int. Cl.
CPC ...
C07K 16/22 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01); A61K 38/17 (2006.01); A61K 38/12 (2006.01); A61K 31/366 (2006.01); A61K 31/5377 (2006.01); A61K 31/436 (2006.01); A61K 31/44 (2006.01); A61K 31/541 (2006.01); A61K 31/496 (2006.01); A61K 38/13 (2006.01); A61K 31/55 (2006.01); A61K 31/12 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01); A61K 31/515 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 31/12 (2013.01); A61K 31/366 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/515 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/55 (2013.01); A61K 38/12 (2013.01); A61K 38/13 (2013.01); A61K 38/16 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); C07K 16/28 (2013.01); C07K 16/2863 (2013.01); G01N 33/5058 (2013.01); A61K 2039/505 (2013.01);
Abstract

Methods of treating glioma are provided. Aspects of the invention include administering a therapeutically-effective amount of an agent that inhibits the activity of one or more neuronal activity-regulated proteins selected from: neuroligin-3, brain-derived neurotrophic factor (BDNF), or brevican, to a patient with a glioma. In certain embodiments, the subject methods involve treating a neurological dysfunction, reducing invasion of a glioma cell into brain tissue, and/or reducing the growth rate of a glioma in the patient. Also provided herein are methods for identifying an agent that modulates the mitotic index of a glial cell, and methods for stimulating the proliferation of a glial cell. Kits that find use in practicing the subject methods are also provided.

Find Patent Forward Citations

Monje-Deisseroth, Michelle. (2019). Method of treating glioma (U.S. Patent No. 10377818). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10377818

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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