The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Dec. 15, 2016
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Robert John Aversa, Watertown, MA (US);

Matthew T. Burger, Belmont, MA (US);

Michael Patrick Dillon, Castro Valley, CA (US);

Thomas A. Dineen, Jr., Somerville, MA (US);

Rajesh Karki, Quincy, MA (US);

Savithri Ramurthy, Arlington, MA (US);

Vivek Rauniyar, Cambridge, MA (US);

Richard Robinson, Cambridge, MA (US);

Patrick James Sarver, Princeton, NJ (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 491/04 (2006.01); C07D 498/04 (2006.01); A61P 35/00 (2006.01); C07D 491/044 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01); C07D 491/044 (2013.01);
Abstract

The present invention provides compounds of Formula (A): (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent, and methods of using the compositions and combinations to treat conditions including cancers.


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