The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

May. 05, 2017
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Lycera Corporation, Ann Arbor, MI (US);

Inventors:

Thomas D. Aicher, Ann Arbor, MI (US);

Kenneth J. Barr, Boston, MA (US);

Blair T. Lapointe, Brookline, MA (US);

Vladimir Simov, Boston, MA (US);

Karin A. Stein, Mountain View, CA (US);

William D. Thomas, San Jose, CA (US);

Peter L. Toogood, Ann Arbor, MI (US);

Chad A. Van Huis, Hartland, MI (US);

Catherine M. White, Boston, MA (US);

Assignees:

Lycera Corporation, Ann Arbor, MI (US);

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 413/06 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 413/06 (2013.01); C07D 471/04 (2013.01);
Abstract

The invention provides tetrahydronaphthyridine and related compounds, pharmaceutical compositions, methods of inhibiting RORγ activity, reducing the amount of IL-17 in a subject, and treating immune disorders and inflammatory disorders using such tetrahydronaphthyridine and related compounds.


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