The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Oct. 28, 2016
University of Tsukuba, Tsukuba-shi, Ibaraki, JP;
Hiroshi Nagase, Tsukuba, JP;
Naoshi Yamamoto, Tsukuba, JP;
Yoko Irukayama, Tsukuba, JP;
Tsuyoshi Saitoh, Tsukuba, JP;
Masashi Yanagisawa, Tsukuba, JP;
Yasuyuki Nagumo, Tsukuba, JP;
UNIVERSITY OF TSUKUBA, Tsukuba-Shi, Ibaraki, JP;
Abstract
The purpose of the present invention is to provide a compound useful as a prophylactic or therapeutic agent for various diseases and symptoms related to orexin receptors, and a medical usage of the same. The present invention provides a morphinan derivative represented by the general formula (I) below or a pharmaceutically acceptable acid addition salt thereof, the morphinan derivative having excellent selectivity for and antagonism against orexin receptors and excellent therapeutic and prophylactic effects on drug dependence, and an orexin receptor antagonist and a therapeutic or prophylactic agent for drug dependence each containing it as an active ingredient.