The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Jul. 18, 2016
Applicant:
New York University, New York, NY (US);
Inventors:
Jin Kim Montclare, New York, NY (US);
Joseph A. Frezzo, Brooklyn, NY (US);
Cynthia Xu, Bridgewater, NJ (US);
Youssef Zaim Wadghiri, New York, NY (US);
Assignee:
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 47/42 (2017.01); A61K 47/64 (2017.01); A61K 49/14 (2006.01); A61K 51/08 (2006.01); C07K 14/78 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
A61K 51/08 (2013.01); A61K 9/5169 (2013.01); A61K 31/704 (2013.01); A61K 47/42 (2013.01); A61K 47/6435 (2017.08); A61K 49/14 (2013.01); C07K 14/78 (2013.01); C07K 2319/00 (2013.01);
Abstract
Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage oligomeric matrix protein and repeats of elastic like peptides. The coiled-coil domain allows delivery of molecules, the elastin-like peptide domain provides thermo-responsive functionality, and a plurality of leucine residues, which can be fluorinated, provide imaging functionality.