The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Jul. 22, 2016
Applicant:

Gmax Biopharm Llc., Hangzhou, CN;

Inventors:

Cheng Zhang, Hangzhou, CN;

Hua Zhang, Hangzhou, CN;

Xiaofeng Wang, Hangzhou, CN;

Chenjiang Yao, Hangzhou, CN;

Yan Jiang, Hangzhou, CN;

Min Wang, Hangzhou, CN;

Xinxin Shi, Hangzhou, CN;

Hao Pan, Hangzhou, CN;

Shuqian Jing, Hangzhou, CN;

Assignee:

Gmax Biopharm LLC., Hangzhou, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12N 5/12 (2006.01); C12N 15/63 (2006.01); C07K 16/26 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); C07K 16/26 (2013.01); C07K 16/28 (2013.01); C12N 5/10 (2013.01); C12N 5/12 (2013.01); C12N 15/63 (2013.01); A61K 2039/505 (2013.01); A61P 9/00 (2018.01); A61P 35/00 (2018.01); C07K 2317/24 (2013.01); C07K 2317/30 (2013.01); C07K 2317/565 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention discloses an antibody specifically binding to a human endothelin receptor and uses thereof, where the antibody can inhibit the functions of the human endothelin receptor. The present invention includes the preparation, cloning, expression, and characterization of the antibody. The present invention can be used to effectively treat pulmonary arterial hypertension, a disease associated with pulmonary arterial hypertension, and a reproductive organ cancer in a human.


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