The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Mar. 20, 2018
Applicant:
Hong Kong Baptist University, Hong Kong, HK;
Inventors:
Assignee:
Hong Kong Baptist University, Hong Kong, HK;
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/12 (2006.01); C07K 7/08 (2006.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); A61K 38/02 (2006.01); A61K 38/22 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
A61K 38/02 (2013.01); A61K 9/0019 (2013.01); A61K 38/005 (2013.01); A61K 38/1796 (2013.01); A61K 38/22 (2013.01); A61P 3/04 (2018.01);
Abstract
Cyclic peptide agonists toward human galanin receptor 2 (GalR2) and galanin receptor 3 (GalR3) based on hidden conformation of spexin solution structure for GalR2 and GalR3-related and spexin-deficient disorders are designed and synthesized. LH101, LH102, and LH101 (Ac) are potent spexin analogs with prolonged action, which can be used in the treatment of GalR2 and GalR3-related diseases and spexin-deficient disorders, such as obesity.