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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10376501 B1

PDFFull Text
Expired
Date of Patent:
Aug. 13, 2019

Filed:

Apr. 25, 2017

Complexes of lumacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them

Applicant:

Druggability Technologies Ip Holdco Limited, Swatar, MT;

Inventors:

Richárd Balázs Kárpáti, Tatabánya, HU;

Betti Szabóné Ordasi, Budapest, HU;

Orsolya Basa-Dénes, Eger, HU;

Erzsébet Réka Angi, Nagykovácsi, HU;

Tamás Jordán, Öcsöd, HU;

László Molnár, Biatorbágy, HU;

Hristos Glavinas, Szeged, HU;

Zsolt Ötvös, Csongrád, HU;

Genovéva Filipcsei, Budapest, HU;

Assignee:

Druggability Technologies IP Holdco Limited, Msida, MT;

Attorneys:

Dennis A. Bennett

Brock D. Levin

Lauren L. Stevens

Primary Examiner:

Jared Barsky

Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/443 (2006.01); A61K 31/192 (2006.01); A61K 9/20 (2006.01); A61K 45/06 (2006.01); A61K 9/14 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
A61K 31/443 (2013.01); A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 9/2013 (2013.01); A61K 9/2072 (2013.01); A61K 31/192 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed herein are pharmaceutically acceptable complex formulations comprising complexes of Lumacaftor, or a salt, or derivative thereof together with complexation agents and, optionally, pharmaceutically acceptable excipients; processes for the preparation thereof and pharmaceutical compositions containing them. The complex formulations have improved dissolution and permeability in fasted and fed state simulation that is expected to deliver full absorption and the elimination of the food effect.

Find Patent Forward Citations

Kárpáti, Richárd Balázs. (2019). Complexes of lumacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them (U.S. Patent No. 10376501). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10376501

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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