The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Jun. 04, 2018
Applicant:
Orion Corporation, Espoo, FI;
Inventors:
Olli Törmäkangas, Turku, FI;
Terhi Heikkinen, Lieto, FI;
Assignee:
Orion Corporation, Espoo, FI;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); A61K 31/277 (2006.01); A61K 31/166 (2006.01); A61K 31/03 (2006.01); C07D 231/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4155 (2013.01); A61K 31/03 (2013.01); A61K 31/166 (2013.01); A61K 31/277 (2013.01); C07D 231/14 (2013.01);
Abstract
The present disclosure relates to solid crystalline forms of N—((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide (I) and the diastereomers thereof, and to methods for preparing such crystalline forms. Compound (I) and the diastereomers thereof are potent androgen receptor (AR) modulators useful as a medicament.