The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Nov. 08, 2016
Applicant:

Teikoku Seiyaku Co., Ltd., Kagawa, JP;

Inventors:

Kunihiko Matsushita, Kagawa, JP;

Mamoru Naruse, Tokushima, JP;

Kenichi Hattori, Tokushima, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 31/4468 (2006.01); A61P 25/04 (2006.01); A61K 47/06 (2006.01); A61K 47/14 (2017.01); A61K 47/32 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7076 (2013.01); A61K 9/0014 (2013.01); A61K 9/7023 (2013.01); A61K 9/7053 (2013.01); A61K 31/4468 (2013.01); A61K 47/06 (2013.01); A61K 47/14 (2013.01); A61K 47/32 (2013.01);
Abstract

A patch for external use which has a laminate structure comprising a substrate and a pressure-sensitive adhesive layer which contains a styrene/isoprene/styrene block copolymer as the base and further contains a tackifier resin consisting of a rosin resin and at least one other tackifier resin, a softening agent consisting of polybutene and liquid paraffin, a fatty acid ester, and fentanyl, characterized in that the weight ratio of the rosin resin to fentanyl is 1 to 5, the weight ratio of the rosin resin to the whole tackifier resin is 0.1 to 0.6, and the tackifier resin accounts for 30 to 60 wt % of the whole pressure-sensitive adhesive layer. The patch is excellent in the permeation of fentanyl through the skin and in storage stability, and is weak in irritation to skin.


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