The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2019
Filed:
Dec. 05, 2017
International Business Machines Corporation, Armonk, NY (US);
Dylan Boday, Tucson, AZ (US);
Willy Chin, Singapore, SG;
Mareva B. Fevre, San Jose, CA (US);
Jeannette Garcia, San Leandro, CA (US);
James L. Hedrick, Pleasanton, CA (US);
Eunice Leong, Singapore, SG;
Nathaniel H. Park, San Jose, CA (US);
Rudy J. Wojtecki, San Jose, CA (US);
Yi Yan Yang, Singapore, SG;
International Business Machines Corporation, Armonk, NY (US);
Institute of Bioengineering and Nanotechnology, Biomedical Sciences Institute, Matrix, SG;
Abstract
The subject matter of this invention relates to block copolymers (BCPs) and, more particularly, to block copolymers capable of self-assembly into nanoparticles for the delivery of hydrophobic cargos. The BCPs include a hydrophobic block that contains a thioether functional group that is susceptible to oxidation, transforming the solubility of the block from hydrophobic to hydrophilic, thereby releasing the hydrophobic cargo of the nanoparticle.