The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
Mar. 01, 2018
Waters Technologies Corporation, Milford, MA (US);
Michael O. Fogwill, South Grafton, MA (US);
Joseph A. Jarrell, Newton Highlands, MA (US);
Joseph D. Michienzi, Plainville, MA (US);
Thomas S. McDonald, Littleton, MA (US);
WATERS TECHNOLOGIES CORPORATION, Milford, MA (US);
Abstract
The present disclosure relates to methodologies, systems and apparatus for controlling pressure in a CO-based chromatography system. A first COpump operates in constant flow mode and delivers COto a chromatography column, and liquid modifier is introduced to the chromatography column according to a gradient. A second COpump is disposed downstream of the column and operates in constant pressure mode to introduce COinto a flow stream at an output of the column. Liquid modifier is also introduced into the flow stream at the output of the column according to a reverse gradient compared to the gradient entering the chromatography column.