The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
May. 21, 2015
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Board of Regents of the University of Texas System, Austin, TX (US);
Irwin D. Bernstein, Seattle, WA (US);
Chengcheng Zhang, Southlake, TX (US);
Mi Deng, Plano, TX (US);
Zhigang Lu, Irving, TX (US);
Junke Zheng, Shanghai, CN;
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
The current disclosure describes methods of expanding precursor cells for hematopoietic transplantation in subjects. The methods culture precursor cells in media containing an immobilized high molecular weight LILRB2 agonist or an LILRB2 agonist in combination with a Notch agonist. The expanded cells can be used to treat a variety of hematopoietic disorders.