The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2019

Filed:

Aug. 30, 2016
Applicants:

Emory University, Atlanta, GA (US);

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Brigham and Women's Hospital, Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Gordon Freeman, Brookline, MA (US);

Arlene Sharpe, Brookline, MA (US);

David M. Dorfman, Brookline, MA (US);

Rafi Ahmed, Atlanta, GA (US);

Daniel Barber, Rockville, MD (US);

E. John Wherry, Havertown, PA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 38/17 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); A61K 31/713 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 31/713 (2013.01); A61K 38/1709 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); G01N 33/505 (2013.01); G01N 33/5011 (2013.01); G01N 33/57484 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/572 (2013.01); C07K 2317/70 (2013.01); C07K 2317/74 (2013.01); C07K 2317/76 (2013.01); G01N 2800/26 (2013.01); Y02A 50/412 (2018.01); Y02A 50/467 (2018.01); Y02A 50/58 (2018.01);
Abstract

The present invention provides methods and compositions for the treatment, prevention, or reduction of persistent infections, such as chronic infections, latent infections, and slow infections and cancer. The methods and compositions of the invention are also useful for the alleviation of one or more symptoms associated with such infections and cancer.


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