The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
May. 20, 2015
Applicant:
Lawrence Livermore National Security, Llc, Livermore, CA (US);
Inventors:
Michael P. Thelen, Danville, CA (US);
Douglas A. Higgins, Point Pleasant, NJ (US);
Thomas L. Ruegg, Berkeley, CA (US);
Assignee:
Lawrence Livermore National Security, LLC, Livermore, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/14 (2006.01); C12N 1/16 (2006.01); C12N 1/20 (2006.01); C12P 7/10 (2006.01); C07K 14/255 (2006.01); C07K 14/395 (2006.01);
U.S. Cl.
CPC ...
C07K 14/255 (2013.01); C07K 14/395 (2013.01); C12N 1/14 (2013.01); C12N 1/16 (2013.01); C12N 1/20 (2013.01); C12P 7/10 (2013.01); C12P 2203/00 (2013.01); Y02E 50/16 (2013.01);
Abstract
The present invention provides for a method of genetically modifying microorganisms to enhance resistance to ionic liquids using a yeast Major Facilitator Superfamily (MFS), or aMFS SmvA Pump or SmvR Regulator, a Small Multidrug Resistance Family (SMR), orYDR090C, polypeptide, host cells genetically modified in accordance with the methods, and methods of using the host cells in a reaction comprising biomass that has been pretreated with ionic liquids.