The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2019

Filed:

Apr. 22, 2016
Applicants:

Paul B. Savage, Mapleton, UT (US);

Thomas E. Jacks, Hillsborough, NJ (US);

Ross A. Miller, Fanwood, NJ (US);

Andrew S. Thompson, Mountainside, NJ (US);

Jared Lynn Randall, Smyrna, NY (US);

Inventors:

Paul B. Savage, Mapleton, UT (US);

Thomas E. Jacks, Hillsborough, NJ (US);

Ross A. Miller, Fanwood, NJ (US);

Andrew S. Thompson, Mountainside, NJ (US);

Jared Lynn Randall, Smyrna, NY (US);

Assignee:

Brigham Young University, Provo, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 41/00 (2006.01); C07J 9/00 (2006.01);
U.S. Cl.
CPC ...
C07J 41/0088 (2013.01); C07J 9/005 (2013.01); C07J 41/0055 (2013.01); C07J 41/0061 (2013.01);
Abstract

Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer, inflammation, and osteogenesis. Ceragenin compounds display broad-spectrum antibacterial activity utilizing a mode of action similar to antimicrobial peptides, but without the high synthesis costs and susceptibility to proteolytic degradation. Ceragenin compounds reproduce the amphiphilic morphology found in many antimicrobial peptides and display potent and diverse biological activities, including anti-bacterial, anti-cancer, anti-inflammatory, bone growth promotion, and wound healing promotion.


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