The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2019

Filed:

Jul. 27, 2016
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Antonella Converso, Elkins Park, PA (US);

Mildred L. Kaufman, Schwenksville, PA (US);

Kevin Rodzinak, Valdosta, PA (US);

Inventors:

Antonella Converso, Elkins Park, PA (US);

Mildred L. Kaufman, Schwenksville, PA (US);

Kevin Rodzinak, Valdosta, PA (US);

Assignee:

Merck, Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/22 (2006.01); A61K 31/4704 (2006.01); C07D 215/56 (2006.01); A61K 45/06 (2006.01); C07D 215/54 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 215/56 (2013.01); A61K 45/06 (2013.01); C07D 215/54 (2013.01); C07D 405/12 (2013.01);
Abstract

The present invention is directed to oxycyanoquinolinone compounds which may be useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.


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