The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
Jul. 12, 2018
Applicants:
National University of Singapore, Singapore, SG;
Institut Pasteur DE Lille, Lille, FR;
Institut National DE LA Santé ET DE LA Recherche Médicale (Inserm), Paris, FR;
Inventors:
Sylvie Claudette Alonso, Singapore, SG;
Annabelle Rui Fen Lim, Singapore, SG;
Camille Locht, Brussels, BE;
Assignees:
National University of Singapore, Singapore, SG;
Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, FR;
Institut Pasteur de Lille, Lille, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/099 (2013.01); A61K 2039/522 (2013.01);
Abstract
A CyaA-deficientmutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced bystrains not deficient in CyaA.