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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10369196 B1

PDFFull Text
Expired
Date of Patent:
Aug. 06, 2019

Filed:

Mar. 14, 2013

Compositions and methods for treating glioblastoma gbm

Applicant:

Vascular Biogenics Ltd., Or Yehuda, IL;

Inventors:

Yael Cohen, Kiryat-Ono, IL;

Livnat Bangio, Petach-Tikva, IL;

Andrew J. Brenner, Boerne, TX (US);

Eyal Breitbart, Hashmonaim, IL;

Assignee:

Vascular Biogenics Ltd., Or Yehuda, IL;

Attorney:

Sterne, Kessler, Goldstein & Fox P.L.L.C.

Primary Examiner:

Anoop K Singh

Assistant Examiner:

Magdalene K Sgagias

Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 38/17 (2006.01); A61K 38/16 (2006.01); C07K 14/705 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61N 5/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A61K 38/162 (2013.01); A61K 39/39558 (2013.01); A61K 48/005 (2013.01); A61N 5/1001 (2013.01); A61N 5/1077 (2013.01); C07K 14/70578 (2013.01); A61K 2039/5258 (2013.01); A61N 2005/1087 (2013.01); C12N 2799/022 (2013.01); Y02E 60/36 (2013.01);
Abstract

Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3; and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.

Find Patent Forward Citations

Cohen, Yael. (2019). Compositions and methods for treating glioblastoma gbm (U.S. Patent No. 10369196). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10369196

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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