The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2019
Filed:
Sep. 25, 2018
Applicant:
Dynavax Technologies Corporation, Berkeley, CA (US);
Inventors:
Cristiana Guiducci, Albany, CA (US);
Robert L. Coffman, Portola Valley, CA (US);
Assignee:
DYNAVAX TECHNOLOGIES CORPORATION, Berkeley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/713 (2006.01); A61K 31/7125 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 9/0073 (2013.01); A61K 31/7125 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of the present disclosure are suitable for treating primary cancer of the lung, as well as metastatic cancer to the lung and extra pulmonary cancers thereof. Additionally, the present disclosure provides polynucleotide Toll-like receptor 9 agonists with immune stimulatory and toxicity profiles suitable for intrapulmonary administration.