The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2019

Filed:

Mar. 14, 2014
Applicant:

Discoverybiomed, Inc., Birmingham, AL (US);

Inventors:

Erik Schwiebert, Birmingham, AL (US);

John Streiff, Birmingham, AL (US);

John Dixon, Leicestershire, GB;

Hongwu Gao, Shanghai, CN;

Joseph P. Ritchie, Vestavia Hills, AL (US);

Eric C. Seales, Birmingham, AL (US);

Deborah Mai, Birmingham, AL (US);

Assignee:

DISCOVERYBIOMED, INC., Birmingham, AL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A01N 43/42 (2006.01); A61K 31/4709 (2006.01); C07D 417/04 (2006.01); C07D 405/04 (2006.01); C07D 413/04 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 491/052 (2006.01); C07D 493/04 (2006.01); C07D 498/04 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01); C07D 405/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 491/052 (2013.01); C07D 493/04 (2013.01); C07D 498/04 (2013.01);
Abstract

Coumarin derivative compounds and methods for the treatment of hyperproliferative diseases, such as cancer, polycystic kidney disease, and fibrosis of different tissues (e.g., idiopathic pulmonary fibrosis), are provided. The methods include administering to a subject a compound as described herein. Also provided are methods for inhibiting the interaction between two or more heat shock protein chaperones in a cell.


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