The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2019

Filed:

Nov. 16, 2012
Applicant:

National Research Council of Canada, Ottawa, CA;

Inventors:

Christopher Reid, Cumberland, RI (US);

Susan M. Logan, Ottawa, CA;

Evguenii Vinogradov, Ottawa, CA;

Andrew Cox, Ottawa, CA;

Jean-Robert Brisson, Ottawa, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/00 (2006.01); A61K 39/08 (2006.01); C07H 11/04 (2006.01); C07H 13/02 (2006.01); C07H 15/04 (2006.01); C12Q 1/04 (2006.01); A61P 31/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0024 (2013.01); A61K 39/08 (2013.01); A61P 31/04 (2018.01); C07H 11/04 (2013.01); C07H 13/02 (2013.01); C07H 15/04 (2013.01); C12Q 1/04 (2013.01); A61K 2039/521 (2013.01); A61K 2039/55566 (2013.01);
Abstract

A novel lipoteichoic acid (LTA) was isolated from, the structure of which is illustrated below wherein n is an integer between 1 and 20, R3 and R4 are independently selected from C 14:0, C 16:0, C 16:1, C 18:0 or C18:1 fatty acid or any combination thereof wherein one of COR3 or COR4 may be replaced by H. Further described are conjugates comprising the novel LTA and vaccines produced using the isolated LTA and the LTA conjugates. The invention also encompasses methods of conferring immunity againstcomprising administering a vaccine of the invention, and methods of detectingusing the isolated LTA of the invention.


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