The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2019

Filed:

Aug. 13, 2015
Applicants:

Calypso Biotech SA, Plan-les-Ouates, CH;

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Yolande Chvatchko Missotten, Confignon, CH;

Laurence Goffin, Ornex, FR;

Olivier Leger, Saint Sixt, FR;

Steven M. Dunn, Sergy, FR;

Christine Power, Thoiry, FR;

Kinsey Maundrell, Chêne Bougeries, CH;

Assignees:

CALYPSO BIOTECH SA, Plan-les-Ouates, CH;

MERCK PATENT GMBH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); G01N 33/53 (2006.01); C12N 15/13 (2006.01); G01N 33/573 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C12Y 304/24035 (2013.01); G01N 33/573 (2013.01); A61K 2039/505 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); G01N 2333/96494 (2013.01);
Abstract

The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.


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