The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2019
Filed:
Apr. 03, 2012
Katsuto Tamai, Osaka, JP;
Takehiko Yamazaki, Osaka, JP;
Tsutomu Kanezaki, Osaka, JP;
Shigeru Sakurai, Osaka, JP;
Yukiko Noguchi, Osaka, JP;
Mayumi Endo, Osaka, JP;
Natsumi Hamabuchi, Osaka, JP;
Kana Naito, Osaka, JP;
Katsuto Tamai, Osaka, JP;
Takehiko Yamazaki, Osaka, JP;
Tsutomu Kanezaki, Osaka, JP;
Shigeru Sakurai, Osaka, JP;
Yukiko Noguchi, Osaka, JP;
Mayumi Endo, Osaka, JP;
Natsumi Hamabuchi, Osaka, JP;
Kana Naito, Osaka, JP;
STEMRIM INC., Osaka, JP;
OSAKA UNIVERSITY, Osaka, JP;
Abstract
(Objective) An objective of the present invention is to provide therapeutic agents that, in association with stimulation of PDGFRα-positive cells such as bone marrow mesenchymal stem cells, promote their mobilization into blood and accumulation in a damaged tissue, and induce tissue regeneration in a living body. (Means for solution) Multiple peptides were synthesized, and the migration-promoting activity of each peptide was evaluated. As a result, the present inventors successfully identified multiple peptides that have migration-promoting activity on a PDGFRα-positive bone marrow mesenchymal stem cell line (MSC-1). Further, the present inventors confirmed that the identified peptides also have migration-promoting activity on skin fibroblasts, which are PDGFRα-positive cells.