The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2019
Filed:
Jun. 26, 2017
Applicants:
Onxeo, Paris, FR;
Institut Curie, Paris, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Inventors:
Jian-Sheng Sun, Saint Maur des Fosses, FR;
Marie Dutreix, L'Hay-les-Roses, FR;
Maria Quanz, Paris, FR;
Assignees:
ONXEO, Paris, FR;
INSTITUT CURIE, Paris, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/53 (2006.01); A61K 47/54 (2017.01); A61K 31/4706 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01); C07H 21/04 (2006.01); A61K 31/713 (2006.01); A61K 47/55 (2017.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/549 (2017.08); A61K 31/4706 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); A61K 47/542 (2017.08); A61K 47/543 (2017.08); A61K 47/551 (2017.08); A61K 47/554 (2017.08); A61K 48/00 (2013.01); A61P 35/00 (2018.01); C07H 21/04 (2013.01);
Abstract
The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.