The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2019
Filed:
Dec. 04, 2014
Applicant:
Realist Pharma, Inc., Toronto, CA;
Inventors:
Horacio Uri Saragovi, Montreal, CA;
Wenyong Tong, San Diego, CA (US);
Assignee:
Horacio Url Saragovi, Montreal QC, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/385 (2006.01); C07H 15/203 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
A61K 39/385 (2013.01); A61K 39/0011 (2013.01); C07H 15/203 (2013.01); C07K 16/3084 (2013.01); C07K 16/44 (2013.01); A61K 2039/575 (2013.01); A61K 2039/645 (2013.01); A61K 2039/70 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01);
Abstract
It is provided a multivalent ganglioside carbohydrate as a therapeutic cancer vaccine. The GD2 and GD3 carbohydrate conjugated disclosed are linked by a spacer to form a multimer which conserves the native structural feature of naturally occurring GD2 or GD3, the tetramer being immunogenic and elicits cytotoxic anti-gangliosides humoral and cellular responses in vivo.