The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2019

Filed:

Jun. 30, 2017
Applicants:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

The United States of America, As Represented BY the Secretary, Dept. of Health and Human Services, Washington, DC (US);

Inventors:

Steven Jules Ackerman, Naperville, IL (US);

Fan Gao Laffey, Chicago, IL (US);

Ben Hitchinson, Chicago, IL (US);

Boris Garnier, Chatanay-malabry, FR;

Vadim Gaponenko, Naperville, IL (US);

Nadya Tarasova, Frederick, MD (US);

Hazem Abdelkarim, Worth, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); A61K 47/10 (2017.01); A61K 47/68 (2017.01); A61P 11/06 (2006.01); A61P 37/08 (2006.01); C07K 14/52 (2006.01); C07K 14/715 (2006.01); A61K 38/00 (2006.01); C07K 14/47 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/195 (2013.01); A61K 47/10 (2013.01); A61K 47/6813 (2017.08); A61P 11/06 (2018.01); A61P 37/08 (2018.01); C07K 14/4703 (2013.01); C07K 14/521 (2013.01); C07K 14/7158 (2013.01); A61K 9/008 (2013.01); A61K 38/00 (2013.01);
Abstract

A C—C chemokine receptor 3 (CCR3) peptide analog that exhibits biased antagonism by binding to and inhibiting ligand-mediated signaling and chemotaxis while promoting the internalization and degradation of CCR3 is provided as is a method of using the peptide analog to treat, prevent, or ameliorate one or more symptoms of an eosinophil- or CCR3-mediated disease or condition.


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