The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2019
Filed:
Mar. 09, 2016
Board of Regents, the University of Texas System, Austin, TX (US);
Florian Muller, Houston, TX (US);
David S. Maxwell, Pearland, TX (US);
William G. Bornmann, Missouri City, TX (US);
Yu-Hsi Lin, Houston, TX (US);
Basvoju A. Bhanu Prasad, Katy, TX (US);
Zhenghong Peng, Missouri City, TX (US);
Duoli Sun, Houston, TX (US);
Nikunj Satani, Houston, TX (US);
M. Emilia Di Francesco, Houston, TX (US);
Ronald A. Depinho, Houston, TX (US);
Barbara Czako, Houston, TX (US);
Federica Pisaneschi, Houston, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
Provided herein are compounds of the formula (I) wherein the variables R, R, R, R, X, X, Y, and Aare as defined herein. Such compounds may be used, for example, for the inhibition of enolase enzymes, including preferential inhibition of one isoenzyme of over one or more of the other isoenzymes. Methods of treatment using these compounds, as well as pharmaceutical compositions thereof, are also provided.