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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10359426 B1

PDFFull Text
Date of Patent:
Jul. 23, 2019

Filed:

Sep. 28, 2017

Use of isocitrate dehydrogenase 1 as a diagnostic and prognostic biomarker and therapeutic target for lung cancers

Applicant:

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Jie He, Beijing, CN;

Fengwei Tan, Beijing, CN;

Zhaoli Chen, Beijing, CN;

Nan Sun, Beijing, CN;

Assignee:

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, CN;

Attorney:

McCoy Russell LLP

Primary Examiner:

J E Angell

Int. Cl.
CPC ...
C12N 15/113 (2010.01); G01N 33/574 (2006.01); C07K 16/40 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); C07K 16/40 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/904 (2013.01);
Abstract

The present invention relates to a method for diagnosing lung cancers such as non-small lung cancer in a subject by using isocitrate dehydrogenase 1 as a diagnostic biomarker. The present invention also relates to a method for predicting the prognosis of the lung cancers such as non-small lung cancer in a subject by using isocitrate dehydrogenase 1 as a prognostic biomarker. The present invention further relates to a method of suppressing proliferation of lung tumor cells in a subject, decreasing growth of lung tumor cells in a subject, or improving survival of a subject with lung cancer by using isocitrate dehydrogenase 1 as a therapeutic target.

Find Patent Forward Citations

He, Jie. (2019). Use of isocitrate dehydrogenase 1 as a diagnostic and prognostic biomarker and therapeutic target for lung cancers (U.S. Patent No. 10359426). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10359426

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