The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Dec. 23, 2016
Applicant:

Scholar Foxtrot Co., Ltd., Mapo-gu, Seoul, KR;

Inventors:

Hyuk-Kee Sung, Seoul, KR;

Jong Seong Kim, Seoul, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/544 (2006.01); C12Q 1/68 (2018.01); G01J 1/46 (2006.01); G01N 21/41 (2006.01); G01N 21/77 (2006.01); G01N 33/68 (2006.01); G01N 33/543 (2006.01); G01N 33/545 (2006.01); G01N 21/552 (2014.01); C08L 33/26 (2006.01);
U.S. Cl.
CPC ...
G01N 33/544 (2013.01); C12Q 1/68 (2013.01); G01J 1/46 (2013.01); G01N 21/41 (2013.01); G01N 21/553 (2013.01); G01N 21/77 (2013.01); G01N 21/7703 (2013.01); G01N 33/545 (2013.01); G01N 33/54373 (2013.01); G01N 33/68 (2013.01); C08L 33/26 (2013.01); G01N 2021/7723 (2013.01); G01N 2021/7776 (2013.01); G01N 2021/7789 (2013.01);
Abstract

Disclosed are a biochip capable of detecting and analyzing multivalent bindings between target protein and binding mediator from monovalent bindings and a method for manufacturing the same. A biochip according to an embodiment comprises: a hydrogel functional layer on which a binding mediator is formed and of which physical properties are changed by a reaction between target protein to be introduced and the binding mediator; and a transducer configured to deliver a displacement signal corresponding to a change in the physical properties of the hydrogel functional layer to an analysis instrument, wherein the reaction is multivalent bindings between the target protein and the binding mediator, and de-swelling occurs in at least a portion of the hydrogel functional layer by the multivalent bindings.


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