The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2019
Filed:
Nov. 18, 2015
Applicant:
Adisseo France S.a.s., Antony, FR;
Inventors:
Thomas Walther, Lacroix-Falgarde, FR;
Helene Cordier, Toulouse, FR;
Christopher Topham, Toulouse, FR;
Isabelle Andre, Toulouse, FR;
Magali Remaud-Simeon, Ramonville, FR;
Robert Huet, Paris, FR;
Jean-Marie Francois, Toulouse, FR;
Assignee:
ADISSEO FRANCE S.A.S., Antony, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/42 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12N 9/12 (2006.01); C12P 9/00 (2006.01); C12P 7/40 (2006.01); C12N 1/21 (2006.01); C12N 15/53 (2006.01); C12N 15/54 (2006.01); C12N 15/70 (2006.01); C07F 9/09 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C07F 9/096 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/1217 (2013.01); C12N 15/70 (2013.01); C12P 7/40 (2013.01); C12P 9/00 (2013.01); C12Y 101/01 (2013.01); C12Y 102/01018 (2013.01); C12Y 207/02004 (2013.01); C12Y 102/01011 (2013.01);
Abstract
A method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway that includes transforming malate into 4-phospho-malate using a malate kinase, then transforming 4-phospho-malate into malate-4-semialdehyde using a malate semialdehyde dehydrogenase, and then transforming malate-4-semialdehyde into 2,4-DHB using a DHB dehydrogenase.