The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Jan. 16, 2018
Applicant:

Kuros Biosciences Ag, Zurich-Schlieren, CH;

Inventors:

Matthias Kinzler, Zurich, CH;

Karl Proba, Zurich, CH;

Assignee:

KUROS BIOSCIENCES AG, Schlieren, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/117 (2010.01); C12N 7/00 (2006.01); C07H 21/04 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C07H 21/04 (2013.01); C12N 7/00 (2013.01); C12N 15/117 (2013.01); A61K 2039/5258 (2013.01); C12N 2310/17 (2013.01); C12N 2320/32 (2013.01); C12N 2795/00034 (2013.01); C12N 2795/18122 (2013.01); C12N 2795/18123 (2013.01);
Abstract

The invention provides processes for the producing compositions comprising (i) a virus-like particle, wherein said virus-like particle is a virus-like particle of an RNA bacteriophage, and (ii) an oligonucleotide, wherein said oligonucleotide is packaged into said virus-like particle. The invention further provides processes for producing nucleotide compositions comprising oligonucleotides suitable to be used in the processes mentioned before. The invention further provides nucleotide compositions obtainable by the processes of the invention and uses thereof. The invention further provides compositions comprising (i) a virus-like particle, wherein said virus-like particle is a virus-like particle of an RNA bacteriophage, and (ii) an oligonucleotide, wherein said oligonucleotide is packaged into said virus-like particle, wherein said compositions are obtainable by the processes of the invention and wherein said compositions preferably comprises a purity of at least 98%, most preferably of at least 99%.


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